Red wine contains many compounds which have a beneficial effect on human health. The aims of this study were to concentrate the valuable components of wine by nanofiltration, to describe the mathematical model of the permeate flux and to estimate the cost of the process. Laboratory-size equipment with a nanofiltration membrane was used for the concentration. The experiments were carried out at constant pressure, different temperatures and different recycle flow rates. The concentration of compounds was analyzed in the permeate and retentate including total acid, total extract, alcohol, sugar, free sulphurous acid, total sulphurous acid, sugarless extract content and volatile acid content. A mathematical modelling and cost analysis of the process were also performed.