The thermal resistance of a model solid-liquid interface in the presence of laminar shear flow is investigated using molecular dynamics simulations. Two model liquids - a monoatomic liquid and a polymeric liquid composed of 20 repeat units - are confined between walls which are modeled as idealized lattice surfaces composed of atoms identical to the monomers. We find that in the absence of a velocity slip (discontinuity) at the solid-fluid interface, the mass flow does not affect the thermal interfacial resistance, but the presence of velocity slip results in an increase in the interfacial thermal resistance by about a factor of two. (c) 2006 Elsevier Ltd. All rights reserved.