In this study, caffeine was extracted from green tea by using molecularly imprinted polymers (MIP) as sorbent materials in solid-phase extraction (SPE), a technique known as MISPE (molecularly imprinted solid-phase extraction). For synthesis of the MIP, caffeine as the template, MAA as the monomer, EGDMA as the crosslinker, and AIBN as the initiator were used. A solution of caffeine (0.2 mg/mL in methanol) was utilized to the solid extraction cartridges following loading, washing, and elution procedures with acetonitrile, methanol, and methanol-acetic acid (90/10, %v/v) as solvents, respectively. This solid-phase extraction protocol was applied to the extraction of caffeine from green tea. A comparison was made between the results obtained with the MIP, blank polymer cartridges, and a traditional C18 reversed-phase cartridge. The recovery obtained using the MIP-based sorbent was almost two times higher than that obtained using a commercially available C18 material. The analysis was performed through high-performance liquid chromatography (HPLC) using a C18 column (5 μm, 250×4.6 mm) with methanol-water (40/60, %v/v) as the mobile phase at a flow rate of 0.5 mL/min.