A practical and divergent synthesis of supported [1,3,5]-triazine dendritic molecules on Wang resin, PEGA resin, SynPhase (TM) Lanterns, and silica gel is described. The alkylamine linkers used allow derivatization with functionality for both synthetic (e.g., supported reagent and scavenger activity) and chemical biology applications. The use of supported intermediates allows differentiation of symmetric linkers without the need for protecting group chemistry. The synthetic route uses inexpensive, readily available starting materials in a straightforward and scaleable strategy. (c) 2006 Wiley Periodicals, Inc.