The synthesis,of immobilized beta-cyclodextrin derivatives onto polyamide-6 fabric is presented. These novel fabrics were prepared by graft-copolymerization of glycidyl methacrylate (GMA) onto polyamide 6 fabric, using a chemical redox system K2S2O8/CuSO(4)center dot 5H(2)O, followed by reaction of beta-cyclodextrins (CD) or monochlorotriazinyl (MCT beta-CD) with the GMA epoxy group. Some biocidal guests were complexed into CD cavity including p-hydroxy benzoic acid, AgNO3-ethanolamine mixture, iodine, N,Ndiethyltoluamide (DETA), citronella, jasmine, and sweet basil. Characterization of the novel fabrics was done by Fourier transform infrared spectroscopy (IR), electron scanning microscopy (SEM), and thermo gravimetric analysis (TGA). The biocidal activity of the grafted fabrics was tested against five strains of microorganisms. (c) 2005 Wiley Periodicals, Inc.