This paper studies state quantization schemes for feedback stabilization of control systems with limited information. The focus is on designing the least destabilizing quantizer subject to a given information constraint. We explore several ways of measuring the destabilizing effect of a quantizer on the closed-loop system, including (but not limited to) the worst-case quantization error. In each case, we show how quantizer design can be naturally reduced to a version of the so-called multicenter problem from locational optimization. Algorithms for obtaining solutions to such problems, all in terms of suitable Voronoi quantizers, are discussed. In particular, an iterative solver is developed for a novel weighted multicenter problem which most accurately represents the least destabilizing quantizer design. A simulation study is also presented.