In this work, a detailed model, along with the numerical procedure to solve this model, was developed for the HF adsorption process on wood chips in a packed-bed reactor. This model is aimed to predict the HF loading distribution, as well as the overall HF loading with respect to the adsorption time. However, the temperature field in the HF reactor may also be obtained using this model, as a function of time. To validate the developed model, the computed overall HF loading profiles were compared with the experimental data acquired previously from a bench-scale, packed-bed reactor filled with big-tooth aspen wood chips, and a good agreement was obtained. By taking advantage of the newly developed adsorption model, the HF loading distribution and temperature field in the bench-scale, packed-bed reactor was examined. It was found that a uniform HF loading distribution and temperature field are always obtained at the end of the adsorption, provided that the adsorption is carried out sufficiently long. This finding is significant, since a uniform HF loading distribution is always desired in operation of the HF adsorption process.