A mathematical model consisting of differential equations for energy, momentum and material exchange is developed for a non-isothermal Venturi-type scrubber. By this model, the effects of heat and mass transfer on droplets concentration distribution and removal efficiency of particulate in a non-isothermal Venturi scrubber can be investigated. In order to approach a realistic model, the liquid film flow on the walls and droplet size distribution are considered. The model is validated by comparing the results of mathematical model by plant and experimental data reported in the literature. The Results section of this work reveals that the inlet humidity and temperature of the gas can affect the removal efficiency of the scrubber.