Pd/Pt supported on pure and doped TiO2 (TiO2-WO3 and TiO2-WO3-SiO2) were prepared and characterized by different techniques (XPS, TEM, XRD, H-2-TPR and TPD of ammonia). These catalysts were investigated in the hydrogenation of tetralin at 6.0 MPa, checking also their thio-tolerance by feeding increasing amounts of dibenzothiophene (DBT, 300 and 1000 wt ppm). The catalytic activity followed the order: Pd/Pt-TiO2 > Pd/Pt-TiO2-WO3-SiO2 > Pd/Pt-TiO2-WO3, evidencing a negative role of a second oxide inside TiO2. The Pd/Pt-TiO2 catalyst showed high activity regardless of reaction conditions (temperature, contact time, H-2/tetralin ratio) together with a good thio-tolerance up to 300 wt ppm of DBT.