A six-bowl carceplex that entraps seven guest molecules, 5(.)(DMSO)(7), was synthesized and characterized. The dynamics of the host shell was studied in solution in the absence and presence of water. A multiple-molecule template was found to drive the formation of 5(.)(DMSO)(x)(.)G((7-x)) (G = DMA, DMF; x = 5-7). Higher selectivity was found for species containing greater numbers of DMSO molecules.