Biotechnology Letters, Vol.26, No.22, 1713-1716, 2004
Improvement of nisin production in pH feed-back controlled, fed-batch culture by Lactococcus lactis subsp. lactis
Nisin production by Lactococcus lactis subsp. lactis in fed-batch culture was doubled by using a pH feed-back controlled method. Sucrose concentration was controlled at 10 g l(-1) giving 5010 IU nisin ml(-1) compared to 2660 IU nisin ml(-1) in batch culture.