In this study the photocatalytic destruction of phenol in an aqueous suspension of illuminated TiO2 was investigated. The experiments were carried out using a Pyrex annular photoreactor. The effects of some parameters such as pH, loading of TiO2, flow rate of O-2 and temperature on the photocatalytic destruction rate of phenol were examined. It was observed that the flow rate of O-2 has no considerable effect on the destruction of phenol over the range of 2-3.5 L min(-1). The photodestruction of phenol followed the pseudo first-order kinetics of the Langmuir-Hinshelwood model giving an activation energy of 16.2 kJ mol(-1).