The operation of chemical reactions and processes in an unsteady-state regime can lead to a better use of energy and matter in the available feedstock. Two examples are the periodic change of the flow direction while operating an exothermic reaction in an adiabatic fixed-bed reactor (reverse-now reactor) and the splitting up of heterogeneously catalyzed oxidation reactions into two separate gas-solid reactions (reduction and oxidation step). In this study, the advantages of both concepts are used and an investigation of the combination for two-step processes (reaction concept) and reverse-now reactors (reactor concept) with chemical reaction engineering techniques are shown.