This paper investigates a hybrid cooling system, utilizing wind-driven cross ventilation and radiational panel cooling in an office setting. The characteristics of the indoor environment are examined using computational fluid dynamics (CFD) simulation, which is coupled with a radiation heat transfer simulation, and HVAC control in which the PMV value for a human model in the center of the room is controlled to attain the target value. The system is devised with an energy-saving strategy, which utilizes stratified room air with a vertical temperature gradient. The cooled air settles down within the lower part of the room, while the hot and humid air passes through the upper region of the room, sweeping out the heat and contaminants generated indoors. This strategy is found to be quite energy-efficient in the intermediate seasons of spring and autumn in Japan. Even under hot and humid outdoor conditions, the hybrid system coupled with radiational cooling would bring significant energy savings are possible compared with a hybrid system coupled with underfloor air-conditioning. (C) 2004 Elsevier B.V. All rights reserved.