The statistical associating fluid theory (SAFT) equation of state is employed for the correlation and prediction of vapor-liquid equilibrium (VLE) of eighteen binary mixtures. These include water with methane, ethane, propane, butane, propylene, carbon dioxide, methanol, ethanol and ethylene glycol (EG), ethanol with ethane, propane, butane and propylene, methanol with methane, ethane and carbon dioxide and finally EG with methane and ethane. Moreover, vapor-liquid equilibrium for nine ternary systems was predicted. The systems are water/ethanol/alkane (ethane, propane, butane), water/ethanol/propylene, water/methanol/carbon dioxide, water/methanol/methane, water/methanol/ethane, water/EG/methane and water/EG/ethane. The results were found to be in satisfactory agreement with the experimental data except for the water/methanol/methane system for which the root mean square deviations for pressure were 60-68% when the methanol concentration in the liquid phase was 60 wt.%. (C) 2004 Elsevier B.V. All rights reserved.