The structural features and catalytic properties of Pt/CeO2 catalysts prepared by liquid phase reduction-deposition techniques with formaldehyde and ethylene glycol as reducing agents, respectively, were investigated. TPR and CO pulse titration measurements revealed that smaller particle size and uniform dispersion of platinum were achieved by modified polyol preparation process, which is beneficial to generate appropriate Pt-O-Ce chemical bonding. XPS analysis further demonstrated the presence of strong metal-support interaction in above Pt/CeO2 catalyst. It was observed that the reducing ability and the solvent effect play important roles in controlling the formation of nuclei as well as its growth rate. The sample prepared by modified polyol method exhibited higher catalytic activities and longer stability for the complete oxidation of dimethyl ether than Pt/CeO2 catalyst prepared by HCHO liquid phase reduction.