In this paper, new design methods will be developed aimed at reduction of cooling water makeup. Reduction in makeup will be achieved by introducing water recovery between wastewater-generating processes and cooling systems. Recognizing that wastewater before or after treatment can replace cooling water makeup, a new design option for the cooling systems will be suggested. As wastewater added to the recirculating cooling water can make the tower bottlenecked, cooling water reuse design can be combined with wastewater recovery. As reuse design of cooling systems allows the cooling tower to take wastewater as makeup, substituting makeup with wastewater can yield water savings, as well as aqueous emissions reduction without overloading the tower. A case study is presented to illustrate the new design methodology.