The cure rate of α, ω-bis[(4-glycidyloxy-3-methoxy)benzylidene-4-aminophenyl]metha ne [liquid crystalline epoxy (LCE) monomer with azomethine]/hexamethylenediamine (HMD) system was studied by differential scanning calorimetry (DSC) analysis. The DSC data were interpreted by the Kissinger and isoconversional methods. The DSC trace of the LCE monomer showed two endotherms at 166.4 and 179.6 ℃, which we associate with LC phase and isotropic transitions, respectively. The DSC curve also showed anionic polymerization above 190 ℃. The dynamic DSC curve for the LCE/HMD system showed that the exothermic peak was separated into two peaks by a weak endotherm at 92 ~ 95 ℃, which was attributed to the LC phase transition, regardless of heating rate. The exothermic peak was related to the cure reaction composed of many competitive reactions between the epoxide and the primary or secondary amines. The activation energy calculated by the Kissinger method was 208.7 kJ/mol, which was higher than those obtained by the isoconversional method because of the different mathematical approach. The activation energy decreased with increasing conversion until α = 0.4, and then it increased after that conversion as a result of increasing diffusion restrictions and formation of liquid crystalline domains.