Heterogeneous asymmetric reaction - Part 35. Enantioselective hydrogenation of 2-oxoglutaric acid over cinchona modified Pt/Al2O3 catalysts

Felfoldi K; Szori K; Bartok M

Applied Catalysis A: General, Vol.251, No.2, 457-460, 2003

DOI10.1016/S0926-860X(03)00366-1 Export Citation

Heterogeneous asymmetric reaction - Part 35. Enantioselective hydrogenation of 2-oxoglutaric acid over cinchona modified Pt/Al2O3 catalysts

Felfoldi K, Szori K, Bartok M

2-Oxoglutaric acid (OGA) may be converted to the important chiral building block (R)-5-oxo-tetrahydrofuran-2-carboxylic acid ((R)-OTC) by enantio selective hydrogenation on cinchona alkaloid modified Pt/alumina catalyst with 92% e.e. in water as solvent. (C) 2003 Elsevier B.V. All rights reserved.

Keywords:enantioselective;hydrogenation;Pt/alumina;cinchonidine-cinchonine;2-oxoglutaric acid