Natural gas must be dehydrated before transmission over a long distance through a pipeline to prevent the condensation of liquid water,to ensure trouble-free operation. This paper deals with the design analysis of dehydration of one million standard cubic meter of natural gas per day using a liquid desiccant, namely, triethylene glycol (TEG), in bubble cap tray towers. The results obtained using the equations that have developed in this paper are compared to the data available in the literature for different gas flow rates, and it is found that they are in very good agreement. The effects of various operating parameters such as pressure, temperature, and TEG circulation rate on the design of the unit are briefly discussed in this article.