The hydrate inhibition potential of four different polymers has been tested in a high-pressure apparatus at high pressures and low temperatures. Aqueous polymer solutions were prepared at 1 wt % concentration. Methane (99.5% purity) was used as hydrate former gas. Hydrate formation rates of the tests were calculated to decide the best inhibitors. A known hydrate inhibitor, poly(N-vinylpyrrolidone) (PVP) and a water-soluble thermoplastic polymer TEO) were determined the best kinetic inhibitors among them.