In this paper, we describe the heat and the power management of a direct methanol fuel cell system. The system consists mainly of a direct methanol fuel cell stack, an anode feed loop with a heat exchanger and on the cathode side, a compressor/expander unit. The model calculations are carried out by analytical solutions for both mass and energy flows. The study is based on measurements on laboratory scale single cells to obtain data concerning mass and voltage efficiencies and temperature dependence of the cell power. In particular, we investigated the influence of water vaporization in the cathode on the heat management of a direct-methanol-fuel-cell (DMFC) system. Input parameters were the stack temperature, the cathode pressure and the air flow rate. It is shown that especially at operating temperatures above 90 degreesC, the combinations of pressure and air flow rate are limited because of heat losses due to vaporization of water in the cathode.