The self-assembly of two complementary components, 5-(4-N-methyl-N-dodecylaminobenzylidene)-2,4,6-(1H,3H)-pyrimidinetrione (1) and 4-amino-2,6-didodecylamino-1,3,5-triazine (2) was found to result in the formation of a hollow supramolecular nanotube with about 6 nm in diameter and hundreds of nanometers in length as observed directly by transmission electron microscope (TEM). X-ray diffraction patterns indicate that a periodical layered structure with a d spacing of 0.49 nm in the nanotube exists. If staining treatment were employed in TEM observations, the self-assembly was found to show a supercoil structure about 300 nm in diameter.