Three isomers of chlorinated polyacrylamides were synthesized by a solution polymerization technique. The prepared polymers were dissolved in acetone to prepare 0.1 and 0.05 wt % solution concentrations. Polymer thin films were then prepared by spin-casting from acetone solutions onto a glass substrate. The prepared films were characterized by Fourier transform infrared (FTIR) spectroscopy and annealed at 80degreesC for 6 h. The surface morphology of the prepared films was studied before and after annealing with an interference microscope to determine the effect of isomerization on the stability of the polymer thin films. The thin film of the polymer with a chlorine atom in the para-position showed better stability due to the ionic interaction with the glass substrate.