The inhibition effects of VOCs and their mixture were studied over Pt/γ-Al2O3 catalyst in supercritical carbon dioxide media. The feed stream was mixed to 300 ppmv of aromatic solvents by air uniformly, as the same method, total concentration of multicomponent of aromatic solvents mixture was kept constant 300 ppmv. The deep conversion of VOCs was increased as the inlet concentration was decreased and the reaction temperature was increased in order benzene > toluene > ethylbenzene > m-xylene > styrene. In mixtures, remarkable effects on reaction rate and selectivity have been evidence; the strongest inhibiting effect was shown by styrene and increases in a reverse order with respect to that of reactivity. In supercritical fluid, the molar density of reaction media was increased with increasing the pressure and decreasing the temperature. The deep conversion of benzene was better than that of toluene and m-xylene, and was increased with the molar density.