10-(adenylalkyl)-3-lauryl-8-azaflavin(Ad-AzaFl) bearing adenine in flavin model compound and N-lauryl-1-((thymyl)alkyl)-1,4-dihydronicotinamide(TNAH) were synthesized by stepwise from uracil, and invetigated about effect of adenine. Adenine in CHCl3 solution dose not have influence on reactivity of flavine, but substrate bearing thymine can act as molecular recognition site at a study of reaction rate.