This work investigated the toxicity, the nuclear magnetic resonance (NMR) spectra, the NMR imaging, and the steady-rheology properties concerning polydimethylsiloxane (PDMS) colloids. These experiments illustrate low toxicity, strong NMR signal intensity, as well as clear images, and render the colloids the potential application as contrast agent for gastrointestinal NMR imaging. The steady-shear rheology data are fitted very well by the model tau = tau(0) + AY(m). According to the theory of Princen and Kiss,(12) we found the yield stresses (tau(0)) of the colloids are proportional to phi(1/3)/D in 0.72 less than or equal to phi less than or equal to 0.81. Based on the model and the definition of the capillary number Ca = tau/(sigma/R), a linear relationship between log(D) and m was discovered if the assumptions that 2Ca sigma/A and Y-eff are constants are satisfied. We also proved these assumptions are rational in the investigated range 0.62 less than or equal to phi less than or equal to 0.81.