Journal of Bioscience and Bioengineering, Vol.89, No.1, 94-96, 2000
Isolation and sequence analysis of plasmid pNO33 in the epsilon-poly-L-lysine-producing actinomycete Streptomyces albulus IFO14147
A high-molecular-size plasmid (37-kb), named pNO33, has been isolated from Streptomyces albulus IFO14147, a producer of epsilon-poly-L-lysine which exhibited antimicrobial activity. The sequence analysis of a 4.6-kb fragment in pNO33 revealed four putative open reading frames, one of which exhibited a significant homology to the bldB gene product involved in morphogenesis and antibiotic production by S. coelicolor.