Membrane and hollow-fiber technologies have widely been used in pure water production, and are increasingly used in conventional water and wastewater treatment for solid-liquid separation. A major challenge to these applications is to prevent or reduce particle fouling so that the membrane or hollow-fiber modules can be operated at a higher permeation flux and over a longer period of time. In this study, a membrane screen/hollow-fiber composite module has been developed for the microfiltration of polydispersed suspensions. The module combines a cylindrical membrane of larger pores as a screen and a bundle of hollow fibers of smaller pores for polishing treatment. Both cross-flow and dead-end filtrations occur in the same module. Experiments were conducted at various concentrations with kaolin particles of size ranging from 0.5 mum to 10 mum. The results showed that the membrane screen effectively removed larger particles from the permeating flow and reduced solid loading to the hollow fibers. As a result, the composite module generated considerably higher permeation flux, as compared to a similar hollow-fiber module without the membrane screen. It was found that larger particle deposition was more significantly affected by the cross flow, and initially deposited particles contributed greater specific resistance to the permeating flow.