The equilibrium loadings of m-xylene from supercritical carbon dioxide on activated carbon are reported. The experimental data were obtained by measuring the outlet concentration of ni-xylene eluted from a column packed with activated carbon until the effluent reached the input concentration. The Freundlich isotherm expression was found to correlate the experimental data satisfactorily. In a second step, the regeneration by supercritical carbon dioxide of activated carbon loaded with m-xylene was investigated. The experimental data demonstrated that the adsorptive capacities of the regenerated activated carbon for m-xylene after many cycles were close to those of the virgin carbon and remained stable. The effects of temperature, pressure, and flow rate on regeneration efficiency were also studied.