Molecular Crystals and Liquid Crystals Science and Technology. Section A. Molecular Crystals and Liquid Crystals, Vol.334, 109-119, 1999
A thorough investigation of the synthetic problems of vic-bis-hydroxylamine - the precursor of Ullman's nitroxides
The products formed in the course of the reduction of 2,3-dimethyl-2,3-dinitrobutane to 2,3-dihydroxylamino-2,3-dimethylbutane in a Zn/NH4Cl/EtOH-H2O system have been investigated. An improved synthesis of 2,3-dihydroxylamino-2,3-dimethylbutane (and its. monosulphate salt) - the key precursor of Ullman's nitroxides - in a Zn/NH4Cl/THF-H2O system is proposed.
Keywords:hydroxylamine derivatives;nitroxides