Graft copolymer gels with different compositions were prepared by the radical polymerization of N-isopropylacrylamide (NIPAAm) and poly(2-vinylpyridine) (P2VP) macromonomers in dioxane with 1 mol% NN'-methylenebisacrylamide (BIS) as the crosslinking agent. The graft copolymer gels were analyzed at different temperatures and pH values. They demonstrated the typical swelling behavior for poly(N-isopropylacrylamide) (PNIPAAm) gels with changing temperature. In addition to the temperature dependent measurements, the graft copolymer with a high P2VP content showed a pronounced swelling transition with changing pH value. By separating the temperature and the pH sensitive component, it was possible to obtain a gel which could be swelled independently in response to temperature and ph.