Micellar cetyltrimethylammonium iodosobenzoate, (CTA)IBA, is highly reactive toward paraoxon (1) and parathion (2). In aqueous solution at PH 9, excess (CTA)IBA mediates their hydrolyses with k(obs)(max) = 0.014 and 0.0030 s(-1), respectively, corresponding to half-lives of 50 s and 3.8 min. Comparisons with other phosphorolytic reagents suggest that (CTA)IBA merits serious consideration for the remediation of paraoxon or parathion contamination.