Design methods of composition control loops of a distillation column, which give small interaction ef-fects, were proposed for two different cases, single- and dual-composition controls, through steady-state simulation study. In case of the single-composition control, the operating conditions could be catagorized into two different ones, on one hand where the desired product is completely recovered without loss and on the other hand where a certain amount of the desired product is allowed to emanate through the other end of the column. Different control loops were suggested depending on the operating conditions for each case. By extending the results of the single-composition con-trols, design methods for dual-composition control loops were also proposed. In this case, the operating conditions could be divided into four different ones and an appropriate control loop which give minimum interaction effects was suggested for each case.