Journal of the American Chemical Society, Vol.121, No.12, 2662-2673, 1999
A broadly applicable method for the efficient synthesis of alpha-O-linked glycopeptides and clustered sialic acid residues
The total syntheses of complex sialylated cell-surface antigens have been accomplished. The target systems include 2.3-STF, STn, 2,6-STF, and glycophorin antigens. In addition,an alpha-O-linked serine glycoside of an entire Lewis blood group (Y) antigen has been assembled.