Preliminary results on the utilization of uric acid in the synthesis of a new group of polyetherols with purine rings are presented. The polyetherols were prepared in a two-stage process. First, hydroxymethyl derivatives of uric acid were obtained from an uric acid and formaldehyde solution. This intermediate was then reacted with ethylene oxide or propylene oxide without any additional solvent. The structure of the intermediates and polyetherols and some of their physical properties were determined, and the possibilities of application of the polyetherols in manufacturing thermostable polyurethane foams were tested.