화학공학소재연구정보센터
Journal of Chemical Physics, Vol.113, No.9, 3909-3915, 2000
Electrophoresis simulated with the cage model for reptation
The cage model for polymer reptation is extended to simulate gel electrophoresis. With increasing electric field strength E, the drift velocity upsilon of a long polymer with length L shows three different regimes: (a) the linear regime where upsilon similar to E/L; (b) the quadratic regime where upsilon similar to E-2, independent of the length of the polymer; and (c) a regime where the velocity decreases exponentionally with E. The transition between regimes (a) and (b) occurs for field strengths E similar to L-1. The transition between regimes (b) and (c) occurs for some value E-h, for which L-1 much less than E-h much less than 1. The behavior in the first two regimes is in agreement with earlier reports on simulations of the Duke-Rubinstein model, and with experimental work on DNA polymers in agarose gel. The third regime is not reported for the Duke-Rubinstein model, probably because in this model, stored length cannot compile into hernias.