The effect of medium perturbation on the polarizabilities of solute molecules in condensed environment are evaluated and analyzed. Some solutes, including Ne, Ar, CH4, Cl-, and H2O, in liquid water and argon were treated employing a supermolecule approach with Monte Carlo simulations and ab initio molecular orbital calculations explicitly considering the solvent molecules. Dielectric solute-solvent interaction was calibrated to derive the intrinsic polarizabilities of solutes. The results revealed a general tendency of decrease in the polarizabilities in solutions from the vacuum values, as much as 13%-18% for neutral solute species and 37% for Cl- in water. The tendency was moderate in liquid argon, 1%-9% reduction for neutral species and 18% for Cl-. About a half of the reduction was attributed to the solute-solvent exchange interaction. Those results are not renormalized with the medium polarization, and thus suitable to model the intermolecular interactions in liquids.