Corynebacterium nitrilophilus amidase was studied with a view to it’s use in ammonium acrylate production. Treatment of whole cells with 1 M acrylamide and 2 M ammonium acrylate solutions significantly reduced amidase activity. Immobilized C. nitrilophilus cells were used in batch and continuous bioreactors. Operation of the continuous reactor was found to be the most convenient way of producing steady state conditions for the study of enzyme stability.