Several methanofullerenes functionalized with either polar or fluorinated groups have been synthesized and their ability to form Langmuir films have been investigated. In both cases, monolayers have been obtained at the gas-water interface. Mixing one of the C-60 derivatives grafted by CF2 groups with an amphiphilic fluorinated compound allows the formation of high-quality Langmuir-Blodgett films, with a well defined intrinsic repeat distance along the normal to the substrate.