The oxygen-18/oxygen-16 ratio of molecular oxygen trapped in ice cores provides a time-stratigraphic marker for transferring the absolute chronology for the Greenland Ice Sheet Project (GISP) II ice core to the Vostok and Byrd ice cores in Antarctica. Comparison of the climate records from these cores suggests that, near the beginning of the last deglaciation, warming in Antarctica began approximately 3000 years before the onset of the warm Bolling period in Greenland. Atmospheric carbon dioxide and methane concentrations began to rise 2000 to 3000 years before the warming began in Greenland and must have contributed to deglaciation and warming of temperate and boreal regions in the Northern Hemisphere.