Injection velocity to a large degree determines the melt injection rate during the injection phase, and it has critical impact on the molded part quality, such as shrinkage, warpage, and impact strength. An injection molding machine operates with different injection velocity profiles, barrel temperatures, molds, and materials. These strongly different molding conditions cause the injection velocity dynamics to vary significantly and to make the control performance of the injection velocity poor with a typical PID controller. A real-time, closed-loop feedback and feedforward control system based on fuzzy logic has been designed, developed, and implemented to control the injection velocity. The fuzzy logic rules of the controller are optimized by analyzing phase plane characteristics. The controller output membership functions are optimized based on a 2(k) factorial design technique. The experimental results reveal that the fuzzy logic-based controller works well with different molds, materials, barrel temperatures, and injection velocity profiles, indicating that the fuzzy logic controller has superior performance over the conventional PID controller in response speed, set-point tracking ability, noise rejection, and robustness.