The synthesis and characterization of novel amphiphilic networks based on dimethylacrylamide and crosslinked by methacrylate telechelic three-arm star polyisobutylene (phi(PIB-MA)(3)) are reported. The networks are characterized by two M-c＇s and possess "homogeneous" and "heterogeneous" crosslinks. The networks swell both in water and n-heptane which indicates a cocontinuous hydrophobic-hydrophilic microarchitecture. Water-swollen networks exhibit higher tensile strengths and elongations, than those made previously with linear MA-PIB-MA＇s of similar overall compositions (i.e., similar to 1.0 versus similar to 0.5 Mpa, and similar to 300% versus similar to 200%, respectively). The enhanced mechanical properties of the new networks are being exploited in biomedical applications.