The synthesis and mesomorphic properties of several dozen 3,6-disubstituted cyclohex-2-enones are described. The compounds were obtained by the condensation of 4-substituted beta-(N,N-dimethylamino)ethylphenyl ketone hydrochlorides (Mannich salts) with 2-alkylacetoacetic esters. The influence of the structure of the reactants, catalysts and solvents on the yield is discussed.