Macromolecules, Vol.33, No.5, 1899-1903, 2000
Dependence of counterion binding on DNA shape as determined by counterion condensation theory
We have computed the fraction of DNA phosphate charge neutralized by condensed counterions for parallel pairs of linear DNA segments, DNA circles, and representative closed-circular supercoiled DNA configurations ranging in length from 42 to 3000 base pairs. We find significant but small uptake of condensed counterions for the more compact structures relative to an isolated linear DNA segment.
Keywords:SUPERCOILED DNA;GEL-ELECTROPHORESIS;BROWNIAN DYNAMICS;SIMULATIONS;VISUALIZATION;EQUILIBRIUM;MODEL;FORCE;SALT