This study analyzes the economic impact that a fluidized-bed reactor (FBR) using immobilized Zymomanas mobilis would have on a plant converting cornstarch into ethanol. The study addresses substituting this new technology into an existing plant or using it for a new plant. We have compared the processing steps required by the FBR with conventional technology, and developed process flow schematics, priced required equipment, and generated plant capital and operating cost estimates. This allowed a cost evaluation between the FBR and traditional technologies, such as well-mixed fed-batch fermentation. The study results indicate that the FBR technology can provide a significant reduction in the production costs of ethanol-a savings of >$0.02/gal if inserted into an existing plant, and a savings of >$0.06/gal if used at a new plant.