화학공학소재연구정보센터
홈 로그인 로그아웃 연락처 사이트맵
Macromolecular Research, Vol.29, No.12, 834-842, December, 2021
DOI10.1007/s13233-021-9095-3  Export Citation
Biomaterials as Antigen Delivery Carrier for Cancer Immunotherapy
Wooram Um1, Anuradha Gupta1, Seok Ho Song1, Chan Ho Kim1, and Jae Hyung Park1, 2, †
  • 1School of Chemical Engineering, College of Engineering, Sungkyunkwan University, 2066 Seobu-ro, Jangan-gu, Suwon 16419, Korea
  • 2Biomedical Institute for Convergence at SKKU (BICS), Sungkyunkwan University, 2066 Seobu-ro, Jangan-gu, Suwon 16419, Korea
E-mail:
Since immunotherapy provides an opportunity to treat metastatic and disseminated tumors, it has become a major treatment strategy for cancer. However, current cancer immunotherapeutics have often exhibited insufficient practical outcomes, primarily attributed to inefficient delivery of tumor-associated antigens to elicit anticancer immunity. To achieve improved therapeutic efficacy, numerous efforts have been made to harness biomaterials for the targeted or sustained delivery of tumor-associated antigens to antigen-presenting cells. In this review, we highlight recent advances in the development of biomaterials to deliver tumor-associated antigens and their therapeutic potential for cancer treatment.
Keywords:biomaterials;antigen delivery;cancer immunotherapy
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