TiO2/PLCL 생분해성 고분자 복합체를 이용한 치아 미백 및 보호효과에 대한 연구

임진익; Jin Ik Lim

Polymer(Korea), Vol.45, No.3, 421-427, May, 2021

DOI10.7317/pk.2021.45.3.421 Export Citation

TiO2/PLCL 생분해성 고분자 복합체를 이용한 치아 미백 및 보호효과에 대한 연구

Tooth Whitening and Protecting Effect Using TiO2/PLCL Biodegradable Polymer Composites

임진익^†

단국대학교 화학공학과

Jin Ik Lim^†

Department of Chemical Engineering, College of Engineering, Dankook University, Jukjeon-dong, Yongin-si, Gyeonggi-do 16890, Korea

E-mail:

초록

치아매니큐어에 적용하기 위한 베이스 레진으로 poly(L-lactide-co-.-caprolactone)(PLCL)을 합성하였고, 락티드와 카프로락톤의 최적 비율을 결정하였다. TiO2는 미백을 위한 안료로 적용되어졌으며, 최적의 TiO2/PLCL 조성비를 위해 탄성회복률, 연필심 경도 측정, 색차계 시험, 접촉각 측정을 진행하였다. 이를 통해 PLCL을 위한 락티드와 카프로락톤의 최적비율은 50:50이였으며, TiO2의 최적 비율은 10%임을 확인하였다. 세포독성 시험 결과 우수한 세포 부착 및 증식 효과를 확인하였고, 천연 치자색소를 이용하여 다양한 노란색 코팅제를 제조해 보았다. 본 연구결과 TiO2/PLCL 복합체는 치아 미백 및 미용 매니큐어의 재료로 적합한 것으로 판단된다.

Poly(L-lactide-co-.-caprolactone) (PLCL) was synthesized, and this was mixed with TiO2 for tooth manicure. A mechanical test was conducted using a tensile strength testing machine and pencil hardness tester; these tests indicated that the optimal molar ratio of lactide in PLCL was 50%. Differences in the surface structures of the films with respect to the hydrophobicity and the whitening effect were examined using a digital microscope, a contact angle meter, and colorimeter. The optimal ratio of TiO2 for the composite was determined to be 10%. The composite coated glass plate yielded a good cell adhesion rate in fibroblasts. The TiO2/PLCL composite manufactured by this simple method can be applied to implantable dental materials, used for tooth whitening, and as a protecting agent during tooth manicures.

Keywords:tooth manicure;whitening;protecting;poly(L-lactide-co-ε-caprolactone);titanium dioxide

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[4] Farawati FAL, Hsu SM, O’Neill E, Neal D, Clark A, J. Prosthet. Dent., 121, 340 (2019)

[5] Junyuan Q, LiZeng W, Licheng T, Ruizhi L, Yiwang CA, Compos. Commun., 13, 107 (2019)

[6] Fatemeh A, Kiana B, Mohammad MI, Amin G, Roya SF, Int. Orthod., 18, 214 (2020)

[7] Mohan N, Westland S, Brunton P, Ellwood R, Pretty IA, Luo WA, J. Dent., 36, 21 (2008)

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[9] Hashimura T, Yamada A, Iwamoto T, Arakaki M, Saito K, Fukumoto S, Pediatr. Dent. J., 23, 44 (2013)

[10] Eric JT, Adv. Drug Deliv. Rev., 112, 88 (2017)

[11] Fabian MG, Mario FDG, J. Prosthet. Dent., 212, 713.e1 2019.

[12] Pitacas HMG, et al., In Vitro. Revista Portuguesa de Estomatologia, Medicina Dentaria e Cirurgia Maxilofacial., 56, 149 2015.

[13] Yue S, Wu J, Zhang Q, Zhang K, Weir MD, Imazato S, Bai Y, Xu HHK, J. Dent., 75, 48 (2018)

[14] Krifka S, Spagnuolo G, Schmalz G, Schweikl HA, Biomaterials, 34, 4555 (2013)

[15] Ma PX, Adv. Drug Deliv. Rev., 60, 184 (2008)

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[18] Chung S, Ingle NP, Montero GA, Kim SH, King MW, Acta Biomater., 6, 1958 (2010)

[19] Kijenska E, Prabhakaran MP, Swieszkowski W, Kurzydlowski KJ, Ramakrishna S, Eur. Polym. J., 50, 30 (2014)

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[21] Padmanabhan NT, John H, J. Environ. Chem. Eng., 8, 104211 (2020)

[22] Fernandez J, Meaurio E, Chaos A, Etxeberria A, Alonso-Varona A, Sarasua JR, Polymer, 54(11), 2621 (2013)

[23] Lim JI, Lim KJ, Lim HN, Lee YK, J. Mater. Sci., 45(19), 5211 (2010)

[24] Wang C, Zeng JS, Wang SA, Yang Z, Huang Q, Chen PX, Zhou SJ, Liu XQ, Appl. Surf. Sci., 255(2), 416 (2008)

[25] Landegren T, Risling M, Persson JKE, Sonde'n A, Int. J. Oral Maxillofac., 39, 705 (2010)

[26] SilvaNunes-Halldorson VD, Steiner RL, Smith GB, Ecotoxicol. Environ. Saf., 57, 162 (2004)

[27] Kim HA, Am. J. Emerg. Med., 26, 1073.e3 2008.

[28] Khan MA, Ahmad R, Srivastava AN, In Vitro Integr. Med. Res., 6, 47 (2017)

[29] Dudic VB, Lang NP, Mombelli A, J. Clin. Periodontol., 26, 341 (1999)