Responsive slippery lubricant-infused porous surfaces (SLIPSs), featuring excellent liquid repelling/sliding capabilities in response to external stimuli, have attracted great attention in smart droplet manipulations. However, most of the reported responsive SLIPSs function under a single stimulus. Here, we report a kind of smart slippery surface capable of on-demand control between sliding and pinning for water droplets via alternately freezing/thawing the stretchable polydimethylsiloxane sheet in different strains. Diverse parameters are quantified to investigate the critical sliding volume of the droplet, including lubricant infusion amount, laser-scanning power, and pillar spacing. By virtue of the cooperation of temperature and force fields acting on the SLIPS, we demonstrate the intriguing applications including controllable chemical reaction and on-demand electrical circuit control. We envision that this dual-responsive surface should providemore possibilities in smart control of microscale droplets, especially in active vaccine-involved biochemical microreactions where a lower temperature is highly favored.