The pulp and paper industry employs processes that produce a large amount of wastewater, resulting in pollution of the environment. In the present study, deinking wastewater was treated using an integrated process of combined coagulation/flocculation, activated sludge process, and Fenton reaction system. The deinking wastewater produced from a large-scale papermaking company was treated. Results indicated that the sedimentation with coagulation and flocculation, used as a pretreatment process, was a preferred option for 55 removal. The semi-extended aeration system for COD and BOD, removal delivered excellent performance. The residual and barely biodegradable pollutants in the wastewater could be efficiently removed by Fenton reactions. The COD, BOD s , and SS total removal efficiencies achieved were 94%, 90%, and 99%, respectively. Measures for control proposed in the present study can efficiently resolve the problems encountered in the operation and can maintain a stable process. The integrated process combining coagulation/flocculation, activated sludge process, and the Fenton reaction system is a favorable option for the long-term operation of the treatment of deinking wastewater. Fenton reactions as a tertiary process applied in deinking wastewater treatment can remove efficiently recalcitrant pollutants and show reliable performance for effluent.